Stoyanov V Will (2009) T-loop Deletion Factor showing speeding aging in Home telomeres - Journal of Anti Aging?

Question

Stoyanov V (Will) has published 2009 the T-loop deletion factor showing speeding aging of Homo telomere diversity and evolution in the Journal of Anti Aging, which has changed our understanding of telomere shortening, but how is this going to affect our future?
The t-loop deletion factor appears to shorten telomeres on their 3’ end so that they can form t-loops. Note that this is happening after the RNA Hayflick primer gap is left, which explains why Hayflicks data was almost correct, however, it is clear now that it makes no difference, as even if we fix the Hayflick problem it will not be a solution for the actual DNA end replication problem, which considering the t-loop deletion factor appear to be the t-loop deletion factor.
During the 2009 international anti aging meeting in Cambridge 2009, there was a presentation of Stoyanov, where he also stated that it was only after he considered the t-loop deletion factor, that he was able to invent a telomere maintenance gene, which actually works on theory. This paper telomere maintenance gene is to be tested in the next few years, but unfortunately this information is restricted. The good news is that Stoyanov said that now as he published the t-loop deletion factor it should be easier to other independent research groups to succeed, as he believes that the reason why everyone has failed in finding telomere maintenance gene (even on paper) is because they as well as him was chasing the ghost of Hayflick. This is the actual reason why he published the t-loop deletion factor, as he is actually looking for independent groups targeting the same problem and perhaps even competition eventually. However currently appears as he leads the only group targeting directly telomere maintenance.


Abstract: http://www.sens.org/index.php?pagename=sens4_abstract&ID=79

Mechanism Image: http://www.flickr.com/photos/professorwhom000/3937528476/sizes/o/

Answer 1

But is this true, has it been proved beyond doubt?

T-loop deletion factor is active in every human, every day speeding aging and cancer, during each cell division. TDF also explains the different ratios of blunt ends.

We look orward to the other groups!

Findings suggest that ORC recruitment by TRF2 contributes to telomere integrity by facilitating efficient telomere DNA replication and preventing the generation of telomere-repeat-containing circles.

Answer 2

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Answer 3

You just fired over almost everyone's head. This is not an Academic discussion blog.

Answer 4

Wow. We are looking forward to hear results.